Extracts of black bean peel and pomegranate peel ameliorate oxidative stress-induced hyperglycemia in mice

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Extracts of black bean peel and pomegranate peel ameliorate oxidative stress-induced hyperglycemia in mice

Oxidative stress has a central role in the progression of diabetes mellitus (DM), which can directly result in the injury of islet β cells and consequent hyperglycemia. The aim of the present study was to evaluate the possible protective effects of black bean peel extract (BBPE), pomegranate peel extract (PPE) and a combination of the two (PPE + BBPE) on streptozotocin-induced DM mice. Oxidativ...

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Neuroprotective and Antioxidant Efficacy of Hydroalcoholic Extracts of Pomegranate Peel

Pomegranate (Punica granatum) peel was extracted with water: ethanol (1:1) at room temperature and the extract was evaluated for antioxidant potential against AAPH induced lipid peroxidation in vitro in mice synaptosomes. In addition, its neuroprotective efficacy against rotenone-induced mortality, motor deficits and oxidative stress in Drosophila melanogaster was also assessed. Extract showed ...

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ژورنال

عنوان ژورنال: Experimental and Therapeutic Medicine

سال: 2014

ISSN: 1792-0981,1792-1015

DOI: 10.3892/etm.2014.2040